The Crazies is an upcoming American horror film directed by Breck Eisner. The story revolves around a town whose water supply has been poisoned by an unknown toxin. It is a remake of the 1973 film of the same name..The Crazies is about the inhabitants of a small Iowa town suddenly plagued by insanity and then death after a mysterious toxin contaminates their water supply. One man, his wife, a nurse, and the sheriff try to survive this plague, but the military is killing everyone on sight. They're going to have to fight their way out, or die by either the plague or the military.